CSAG2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CSAG2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSAG2-associated genes across cancer lineages are MIR5003, ATG3P1, and TAB2-AS1. Each is linked with CSAG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSAG2-to-partner and partner-to-CSAG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5003 grouped by CSAG2-low versus CSAG2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSAG2→partner) and Y-score (partner→CSAG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR5003 →+0.700+5.133<.001.00832
UCECATG3P1 →+0.182+6.123<.001.00231
UCECTAB2-AS1 →+0.182+5.133.002.00831
UCECTUBB3P2 →+0.426+5.694<.001.00331
UCECOR6M2P →+0.182+5.081.009.00831
UCECNUDT4P2 →+0.189+5.484<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MIR5003 by CSAG2 expression — UCEC

Box plot of MIR5003 in CSAG2-low vs CSAG2-high samples in UCEC.

Explore this box plot interactively →

Exploration