CS

Across TCGA cell cohorts, CS RNA expression is significantly associated with the go_rna of many other GO terms, with 4,900 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CS-associated GO terms across cancer lineages are Defense response to bacterium, DNA replication initiation, and rRNA 5'-end processing. Each is linked with CS in more than 16 cancer types. Because this analysis shows association rather than direction, both CS-to-partner and partner-to-CS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Defense response to bacterium grouped by CS-low versus CS-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CS→partner) and Y-score (partner→CS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Defense response to bacterium →	-0.130	-0.675	<.001	<.001	2	17
SOFT_TISSUE	DNA replication initiation →	+0.175	+0.733	<.001	.004	3	16
LIVER	rRNA 5'-end processing →	+0.173	+0.428	.002	.009	3	15
BONE	DNA replication checkpoint signaling →	+0.157	+0.673	<.001	<.001	3	15
BONE	Regulation of DNA-templated DNA replication →	+0.154	+0.994	<.001	<.001	3	15
SOFT_TISSUE	Lagging strand elongation →	+0.211	+0.994	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,900 associations by consensus.

Defense response to bacterium by CS expression — OESOPHAGUS

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