Across TCGA patient cohorts, CRYZL1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,203 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CRYZL1-associated genes across cancer lineages are CXCL1, AQP9, and NAMPT. Each is linked with CRYZL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CRYZL1-to-partner and partner-to-CRYZL1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYZL1→partner) and Y-score (partner→CRYZL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CXCL1 →	-2.328	-0.278	<.001	.002	3	6
HNSC	AQP9 →	-1.449	-0.435	<.001	<.001	3	5
LSCC	NAMPT →	-0.887	-0.174	.001	.004	3	5
UCEC	HNMT →	+1.074	+0.337	<.001	<.001	3	5
LSCC	ME3 →	+0.644	+0.167	<.001	<.001	3	5
HNSC	FPR2 →	-1.205	-0.456	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,203 associations by consensus.

Exploration

CRYZL1 survival (RNA) · tumor vs normal (RNA) · all CRYZL1 data types