CRYL1

Across TCGA patient cohorts, CRYL1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,725 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CRYL1-associated genes across cancer lineages are HMGA1, CDCA5, and CENPH. Each is linked with CRYL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CRYL1-to-partner and partner-to-CRYL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYL1 versus HMGA1 in BRCA, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYL1→partner) and Y-score (partner→CRYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HMGA1 →	-1.001	-0.373	.001	.006	3	9
BRCA	CDCA5 →	-1.056	-0.501	<.001	<.001	3	9
LSCC	CENPH →	-0.976	-0.305	<.001	<.001	3	9
LUAD	EXO1 →	-0.966	-0.369	<.001	<.001	3	9
BRCA	KPNA2 →	-0.795	-0.568	<.001	<.001	3	9
BRCA	UBE2T →	-1.062	-0.572	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,725 associations by consensus.

CRYL1 vs HMGA1 — BRCA

Explore this scatter interactively →