Across TCGA patient cohorts, CRYGS protein abundance is significantly associated with the RNA expression of many other genes, with 891 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRYGS-associated genes across cancer lineages are SLC27A3, STOM, and FAM216A. Each is linked with CRYGS in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYGS-to-partner and partner-to-CRYGS results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYGS→partner) and Y-score (partner→CRYGS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC27A3 →	-1.200	-1.333	.008	<.001	3	1
LSCC	STOM →	-0.709	-1.333	.008	<.001	3	1
LSCC	FAM216A →	-0.419	-1.223	<.001	.002	3	1
LSCC	MIR503 →	+1.860	+2.791	<.001	.003	3	1
LSCC	GDI2P1 →	+0.106	+2.791	<.001	.003	3	1
LSCC	LINC02779 →	+0.170	+2.921	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 891 associations by consensus.

Exploration

CRYGS survival (RNA) · tumor vs normal (RNA) · all CRYGS data types