CRYGN

Across TCGA patient cohorts, CRYGN protein abundance is significantly associated with the RNA expression of many other genes, with 571 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CRYGN-associated genes across cancer lineages are DES, GALNT16, and CLN5. Each is linked with CRYGN in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYGN-to-partner and partner-to-CRYGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYGN versus DES in HNSC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYGN→partner) and Y-score (partner→CRYGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DES →	+3.755	+0.652	.006	.005	3	2
HNSC	GALNT16 →	+0.559	+0.879	.004	<.001	3	1
HNSC	CLN5 →	+0.617	+0.783	.001	<.001	3	1
HNSC	PTGDS →	+1.016	+0.714	.001	.006	3	1
HNSC	CXCL12 →	+1.864	+0.801	.003	.003	3	1
HNSC	ERLIN1 →	-0.463	-0.689	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 571 associations by consensus.

CRYGN vs DES — HNSC

Explore this scatter interactively →