CRYGB

Across TCGA cell cohorts, CRYGB RNA expression is significantly associated with the go_rna of many other GO terms, with 124 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CRYGB-associated GO terms across cancer lineages are Establishment or maintenance of transmembrane electrochemical gradient, Positive regulation of cell communication by electrical coupling, and Positive regulation of nitric oxide mediated signal transduction. Each is linked with CRYGB in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYGB-to-partner and partner-to-CRYGB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of transmembrane electrochemical gradient grouped by CRYGB-low versus CRYGB-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYGB→partner) and Y-score (partner→CRYGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Establishment or maintenance of transmembrane electrochemical gradient →	-0.180	-0.015	.004	.006	3	1
SKIN	Positive regulation of cell communication by electrical coupling →	-1.164	-0.015	.004	.006	3	1
SKIN	Positive regulation of nitric oxide mediated signal transduction →	+0.218	+0.016	.002	.004	3	1
SKIN	Regulation of peptidyl-threonine phosphorylation →	-0.171	-0.027	<.001	.007	3	1
SKIN	Negative regulation of peptidyl-threonine phosphorylation →	-0.168	-0.015	.002	.006	3	1
SKIN	Positive regulation of lipid storage →	-0.125	-0.015	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 124 associations by consensus.

Establishment or maintenance of transmembrane electrochemical gradient by CRYGB expression — SKIN

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