CRYGB

Across TCGA cell cohorts, CRYGB mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CRYGB-associated genes across cancer lineages are WNT9B, CNGA2, and OR1L3. Each is linked with CRYGB in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYGB-to-partner and partner-to-CRYGB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WNT9B grouped by CRYGB-low versus CRYGB-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYGB→partner) and Y-score (partner→CRYGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	WNT9B →	+0.713	+4.276	<.001	.007	3	1
BLOOD_Leukemia	CNGA2 →	+0.074	+4.539	<.001	.007	3	1
SKIN	OR1L3 →	+0.029	+5.415	<.001	.004	3	1
BLOOD_Leukemia	TRIL →	+0.269	+4.350	<.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

WNT9B by CRYGB expression — BLOOD_Leukemia

Explore this box plot interactively →