CRYGA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRYGA RNA expression is significantly associated with the protein abundance of many other proteins, with 4,782 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRYGA-associated proteins across cancer lineages are SCAI, IRF2BP1, and LMNA_S94. Each is linked with CRYGA in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYGA-to-partner and partner-to-CRYGA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYGA versus SCAI in GBM, with a Pearson correlation of 0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYGA→partner) and Y-score (partner→CRYGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSCAI →+0.316+0.403.001.00532
OVIRF2BP1 →+0.291+0.107.001.00332
OVLMNA_S94 →-0.962-0.105.003.00332
GBMNCF2 →-0.525-0.668.003.00132
OVFCER1G →-0.537-0.101.002.00632
UCECALG2 →-0.312-0.191<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,782 associations by consensus.

CRYGA vs SCAI — GBM

Per-sample scatter of CRYGA vs SCAI in GBM (Pearson r = 0.24).

Explore this scatter interactively →

Exploration