Across TCGA patient cohorts, CRYGA RNA expression is significantly associated with the go_rna of many other GO terms, with 6,677 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CRYGA-associated GO terms across cancer lineages are Establishment of protein localization to mitochondrial membrane, rRNA modification, and Positive regulation of double-strand break repair via homologous recombination. Each is linked with CRYGA in more than 11 cancer types. Because this analysis shows association rather than direction, both CRYGA-to-partner and partner-to-CRYGA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYGA→partner) and Y-score (partner→CRYGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Establishment of protein localization to mitochondrial membrane →	+0.101	+0.202	<.001	<.001	3	12
STAD	rRNA modification →	+0.085	+0.223	<.001	<.001	3	12
STAD	Positive regulation of double-strand break repair via homologous recombination →	+0.083	+0.180	<.001	<.001	3	11
STAD	DNA replication →	+0.093	+0.210	<.001	<.001	3	11
STAD	tRNA processing →	+0.088	+0.207	<.001	<.001	3	11
STAD	rRNA methylation →	+0.079	+0.213	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,677 associations by consensus.

Exploration

CRYGA survival (RNA) · tumor vs normal (RNA) · all CRYGA data types