CRYGA

Across TCGA cell cohorts, CRYGA RNA expression is significantly associated with the mutation status of many other genes, with 30 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CRYGA-associated genes across cancer lineages are ABCA12, MAP1B, and ADRA2A. Each is linked with CRYGA in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYGA-to-partner and partner-to-CRYGA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCA12 grouped by CRYGA-low versus CRYGA-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYGA→partner) and Y-score (partner→CRYGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ABCA12 →	+4.614	+0.025	.004	<.001	3	2
OESOPHAGUS	MAP1B →	+4.906	+0.043	.006	<.001	3	1
OESOPHAGUS	ADRA2A →	+4.906	+0.043	.006	<.001	3	1
OESOPHAGUS	PARP14 →	+4.906	+0.043	.006	<.001	3	1
OESOPHAGUS	GDF3 →	+4.906	+0.043	.006	<.001	3	1
OESOPHAGUS	H1-5 →	+4.906	+0.043	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

ABCA12 by CRYGA expression — PANCREAS

Explore this box plot interactively →