CRYBG3

Across TCGA patient cohorts, CRYBG3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,476 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRYBG3-associated genes across cancer lineages are PMF1, FPR2, and MRC1. Each is linked with CRYBG3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CRYBG3-to-partner and partner-to-CRYBG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYBG3 versus PMF1 in HNSC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBG3→partner) and Y-score (partner→CRYBG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PMF1 →	-0.528	-0.171	<.001	<.001	3	6
GBM	FPR2 →	+1.413	+0.308	<.001	<.001	3	6
GBM	MRC1 →	+2.049	+0.461	<.001	<.001	3	6
GBM	C12orf65 →	-0.348	-0.306	<.001	.001	3	6
LSCC	CARD6 →	+0.832	+0.340	<.001	.001	3	6
OV	NFKBIZ →	+1.073	+0.359	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,476 associations by consensus.

CRYBG3 vs PMF1 — HNSC

Explore this scatter interactively →