CRYBG3

Across TCGA cell cohorts, CRYBG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,753 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CRYBG3-associated GO terms across cancer lineages are Regulation of intracellular protein transport, Vesicle-mediated transport to the plasma membrane, and Protein targeting to vacuole. Each is linked with CRYBG3 in more than 9 cancer types. Because this analysis shows association rather than direction, both CRYBG3-to-partner and partner-to-CRYBG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular protein transport grouped by CRYBG3-low versus CRYBG3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBG3→partner) and Y-score (partner→CRYBG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of intracellular protein transport →	+0.073	+1.162	<.001	<.001	3	9
BONE	Vesicle-mediated transport to the plasma membrane →	+0.068	+1.266	<.001	<.001	3	9
BONE	Protein targeting to vacuole →	+0.091	+2.113	<.001	<.001	2	10
URINARY_TRACT	Negative regulation of cilium assembly →	+0.067	+0.972	.001	.004	2	10
KIDNEY	Schwann cell development →	+0.121	+0.617	<.001	.002	3	9
BONE	Post-Golgi vesicle-mediated transport →	+0.074	+1.698	.003	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,753 associations by consensus.

Regulation of intracellular protein transport by CRYBG3 expression — BREAST

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