CRYBG2

Across TCGA patient cohorts, CRYBG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,091 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CRYBG2-associated proteins across cancer lineages are CRYBG2_S441, CRYBG2_S474, and CRYBG2_S491. Each is linked with CRYBG2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CRYBG2-to-partner and partner-to-CRYBG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYBG2 versus CRYBG2_S441 in LSCC, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBG2→partner) and Y-score (partner→CRYBG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CRYBG2_S441 →	+1.292	+1.297	<.001	<.001	3	6
BRCA	CRYBG2_S474 →	+1.374	+0.780	<.001	<.001	3	6
LSCC	CRYBG2_S491 →	+1.391	+1.639	.003	.001	3	6
LSCC	CRYBG2_S508 →	+1.598	+1.366	<.001	<.001	3	6
OV	PODXL →	-0.823	-0.571	.003	<.001	2	6
HNSC	ZNF185 →	+0.781	+1.065	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,091 associations by consensus.

CRYBG2 vs CRYBG2_S441 — LSCC

Explore this scatter interactively →