CRYBG2

Across TCGA patient cohorts, CRYBG2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,294 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CRYBG2-associated genes across cancer lineages are CSTB, TGM5, and PLCH1. Each is linked with CRYBG2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRYBG2-to-partner and partner-to-CRYBG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYBG2 versus CSTB in HNSC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBG2→partner) and Y-score (partner→CRYBG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CSTB →	+1.145	+0.481	<.001	<.001	3	4
HNSC	TGM5 →	+1.066	+0.442	<.001	<.001	3	3
HNSC	PLCH1 →	-0.915	-0.405	<.001	<.001	3	3
UCEC	IL1A →	+1.344	+0.947	<.001	<.001	3	3
UCEC	HMGN3 →	-0.670	-0.816	.003	<.001	3	3
UCEC	LYPD3 →	+2.001	+1.112	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,294 associations by consensus.

CRYBG2 vs CSTB — HNSC

Explore this scatter interactively →