CRYBG2

Across TCGA cell cohorts, CRYBG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,946 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible CRYBG2-associated GO terms across cancer lineages are Bundle of His cell to Purkinje myocyte communication, Maintenance of blood-brain barrier, and Sensory perception of salty taste. Each is linked with CRYBG2 in more than 11 cancer types. Because this analysis shows association rather than direction, both CRYBG2-to-partner and partner-to-CRYBG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bundle of His cell to Purkinje myocyte communication grouped by CRYBG2-low versus CRYBG2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBG2→partner) and Y-score (partner→CRYBG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Bundle of His cell to Purkinje myocyte communication →	+0.902	+0.716	.002	.002	3	12
LUNG_NSCLC_LUSC	Maintenance of blood-brain barrier →	+0.199	+1.659	<.001	<.001	3	12
BREAST	Sensory perception of salty taste →	+0.996	+1.054	.002	.001	3	11
URINARY_TRACT	Regulation of action potential →	+0.165	+3.742	<.001	<.001	3	11
STOMACH	NMDA selective glutamate receptor signaling pathway →	+0.329	+2.081	<.001	<.001	3	11
PANCREAS	Cellular response to indole-3-methanol →	+0.211	+2.192	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,946 associations by consensus.

Bundle of His cell to Purkinje myocyte communication by CRYBG2 expression — SOFT_TISSUE

Explore this box plot interactively →