CRYBG1

Across TCGA patient cohorts, CRYBG1 mutation is significantly associated with the RNA expression of many other genes, with 3,775 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRYBG1-associated genes across cancer lineages are LINC02528, HK3, and GFI1. Each is linked with CRYBG1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRYBG1-to-partner and partner-to-CRYBG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02528 grouped by CRYBG1-low versus CRYBG1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBG1→partner) and Y-score (partner→CRYBG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LINC02528 →	+0.522	+3.881	<.001	.002	3	4
UCEC	HK3 →	+0.616	+2.102	<.001	<.001	3	4
UCEC	GFI1 →	+0.458	+1.828	<.001	<.001	3	4
BLCA	RN7SKP270 →	+0.044	+4.463	<.001	.003	3	4
BLCA	RNU6-1256P →	+0.239	+2.984	<.001	.003	3	4
SKCM	RPL35AP33 →	+0.049	+1.296	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,775 associations by consensus.

LINC02528 by CRYBG1 expression — LIHC

Explore this box plot interactively →