CRYBG1

Across TCGA cell cohorts, CRYBG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,831 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CRYBG1-associated GO terms across cancer lineages are Negative regulation of cytoskeleton organization, Membrane raft assembly, and Small GTPase-mediated signal transduction. Each is linked with CRYBG1 in more than 10 cancer types. Because this analysis shows association rather than direction, both CRYBG1-to-partner and partner-to-CRYBG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cytoskeleton organization grouped by CRYBG1-low versus CRYBG1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBG1→partner) and Y-score (partner→CRYBG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of cytoskeleton organization →	+0.045	+1.333	<.001	<.001	3	11
SOFT_TISSUE	Membrane raft assembly →	+0.168	+1.133	<.001	<.001	3	10
LUNG_SCLC	Small GTPase-mediated signal transduction →	+0.047	+1.496	<.001	<.001	3	10
OVARY	Neuron projection organization →	+0.127	+1.554	<.001	<.001	3	9
SOFT_TISSUE	Cytoplasmic pattern recognition receptor signaling pathway →	+0.076	+1.607	<.001	<.001	3	9
PANCREAS	Hemidesmosome assembly →	+0.188	+1.615	.004	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,831 associations by consensus.

Negative regulation of cytoskeleton organization by CRYBG1 expression — BLOOD_Lymphoma

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