CRYBA1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRYBA1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,317 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CRYBA1-associated genes across cancer lineages are SPARC, CALD1, and COL5A2. Each is linked with CRYBA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CRYBA1-to-partner and partner-to-CRYBA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYBA1 versus SPARC in OV, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBA1→partner) and Y-score (partner→CRYBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSPARC →+1.683+0.530<.001<.001310
OVCALD1 →+1.076+0.456<.001<.001310
OVCOL5A2 →+2.008+0.474<.001<.001310
OVLGALS1 →+1.055+0.478<.001<.00139
OVPDGFRL →+1.212+0.436<.001<.00139
OVCCN4 →+1.328+0.432<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,317 associations by consensus.

CRYBA1 vs SPARC — OV

Per-sample scatter of CRYBA1 vs SPARC in OV (Pearson r = 0.67).

Explore this scatter interactively →

Exploration