CRYBA1

Across TCGA cell cohorts, CRYBA1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CRYBA1-associated genes across cancer lineages are C10orf53. Each is linked with CRYBA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYBA1-to-partner and partner-to-CRYBA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by CRYBA1-low versus CRYBA1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBA1→partner) and Y-score (partner→CRYBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C10orf53 →	+0.024	+5.217	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

C10orf53 by CRYBA1 expression — LARGE_INTESTINE

Explore this box plot interactively →