CRYAA2

Across TCGA patient cohorts, CRYAA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,809 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CRYAA2-associated GO terms across cancer lineages are Spindle organization, Cell cycle G2/M phase transition, and Regulation of microtubule cytoskeleton organization. Each is linked with CRYAA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CRYAA2-to-partner and partner-to-CRYAA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle organization grouped by CRYAA2-low versus CRYAA2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYAA2→partner) and Y-score (partner→CRYAA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Spindle organization →	+0.040	+0.015	<.001	<.001	3	8
STAD	Cell cycle G2/M phase transition →	+0.036	+0.015	<.001	.001	3	8
STAD	Regulation of microtubule cytoskeleton organization →	+0.032	+0.016	<.001	<.001	3	7
THYM	Positive regulation of mitotic cell cycle phase transition →	+0.035	+0.029	<.001	<.001	3	7
STAD	Microtubule cytoskeleton organization involved in mitosis →	+0.042	+0.017	<.001	<.001	3	7
STAD	Regulation of DNA replication →	+0.039	+0.018	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,809 associations by consensus.

Spindle organization by CRYAA2 expression — STAD

Explore this box plot interactively →