CRYAA2

Across TCGA cell cohorts, CRYAA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 817 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CRYAA2-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Epigenetic regulation of gene expression, and Regulation of myoblast fusion. Each is linked with CRYAA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRYAA2-to-partner and partner-to-CRYAA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by CRYAA2-low versus CRYAA2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYAA2→partner) and Y-score (partner→CRYAA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.091	+0.084	<.001	<.001	3	4
BLOOD_Leukemia	Epigenetic regulation of gene expression →	+0.021	+0.039	.009	.005	3	4
OVARY	Regulation of myoblast fusion →	+0.069	+0.055	<.001	.001	3	4
OVARY	Autophagy of mitochondrion →	+0.066	+0.066	.001	.003	3	4
URINARY_TRACT	Negative regulation of gene expression, epigenetic →	+0.030	+0.040	.008	.002	2	4
UPPER_AERODIGESTIVE_TRACT	Zinc ion import into lysosome →	-0.188	-0.059	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 817 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by CRYAA2 expression — OVARY

Explore this box plot interactively →