CRY1

Across TCGA patient cohorts, CRY1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,701 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CRY1-associated proteins across cancer lineages are TRIM21_S266, RHBDF2, and TRIM21. Each is linked with CRY1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRY1-to-partner and partner-to-CRY1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRY1 versus TRIM21_S266 in GBM, with a Pearson correlation of -0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRY1→partner) and Y-score (partner→CRY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM21_S266 →	-0.486	-0.578	.002	.003	3	5
GBM	RHBDF2 →	-0.447	-0.476	.002	.001	3	5
GBM	TRIM21 →	-0.317	-0.489	.005	.001	3	4
OV	SMARCD1 →	+0.381	+0.456	.009	.009	3	4
OV	LYN →	-0.396	-0.680	<.001	<.001	3	4
GBM	MEST →	+0.592	+0.522	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,701 associations by consensus.

CRY1 vs TRIM21_S266 — GBM

Explore this scatter interactively →