CRY1

Across TCGA cell cohorts, CRY1 mutation is significantly associated with the mutation status of many other genes, with 2,226 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CRY1-associated genes across cancer lineages are DIP2C, YLPM1, and SCN1A. Each is linked with CRY1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRY1-to-partner and partner-to-CRY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DIP2C grouped by CRY1-low versus CRY1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRY1→partner) and Y-score (partner→CRY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DIP2C →	+2.602	+3.528	.003	.003	1	5
SKIN	YLPM1 →	+2.450	+3.402	.005	.005	1	4
BLOOD_Lymphoma	SCN1A →	+3.440	+5.016	<.001	<.001	1	4
BLOOD_Leukemia	MYH10 →	+4.321	+5.285	.005	.005	1	4
BLOOD_Leukemia	SFMBT2 →	+5.321	+5.894	.002	.002	1	4
LARGE_INTESTINE	MIDEAS →	+2.043	+3.693	.009	.009	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,226 associations by consensus.

DIP2C by CRY1 expression — SKIN

Explore this box plot interactively →