CRTC2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRTC2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,937 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CRTC2-associated genes across cancer lineages are ASH1L, TBX19, and PRUNE1. Each is linked with CRTC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CRTC2-to-partner and partner-to-CRTC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRTC2 versus ASH1L in BRCA, with a Pearson correlation of 0.22.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRTC2→partner) and Y-score (partner→CRTC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAASH1L →+0.528+0.206.002.00133
BRCATBX19 →+0.700+0.165.001.00633
BRCAPRUNE1 →+0.517+0.202<.001.00133
UCECGABPB2 →+0.552+0.316<.001<.00133
GBMNEK7 →+0.458+0.184.004.00533
BRCATADA1 →+0.525+0.226<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,937 associations by consensus.

CRTC2 vs ASH1L — BRCA

Per-sample scatter of CRTC2 vs ASH1L in BRCA (Pearson r = 0.22).

Explore this scatter interactively →

Exploration