CRTC1

Across TCGA patient cohorts, CRTC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,688 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRTC1-associated proteins across cancer lineages are HDGFL2, MYEF2_S17, and PRPF31. Each is linked with CRTC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRTC1-to-partner and partner-to-CRTC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRTC1 versus HDGFL2 in BRCA, with a Pearson correlation of 0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRTC1→partner) and Y-score (partner→CRTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL2 →	+0.304	+0.486	.002	.004	3	5
LSCC	MYEF2_S17 →	+0.891	+0.459	.001	.002	3	5
PDAC	PRPF31 →	+0.260	+0.322	<.001	<.001	3	5
GBM	SPIN1 →	+0.439	+0.742	.001	<.001	3	5
LSCC	SUGP2 →	+0.395	+0.452	.006	.001	3	5
HNSC	RO60 →	+0.291	+0.731	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,688 associations by consensus.

CRTC1 vs HDGFL2 — BRCA

Explore this scatter interactively →