CRTC1

Across TCGA patient cohorts, CRTC1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,731 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRTC1-associated genes across cancer lineages are SLC25A42, ZNF708, and ZNF540. Each is linked with CRTC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CRTC1-to-partner and partner-to-CRTC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRTC1 versus SLC25A42 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRTC1→partner) and Y-score (partner→CRTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SLC25A42 →	+0.616	+0.208	<.001	<.001	3	6
HNSC	ZNF708 →	+0.652	+0.260	.005	<.001	3	6
BRCA	ZNF540 →	+0.879	+0.435	<.001	<.001	3	6
LUAD	ZNF56 →	+0.479	+0.164	.001	.001	3	6
HNSC	ZNF14 →	+0.824	+0.204	<.001	.004	3	5
BRCA	ZNF91 →	+0.833	+0.433	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,731 associations by consensus.

CRTC1 vs SLC25A42 — OV

Explore this scatter interactively →