CRTAM

Across TCGA pan-cancer cohorts, CRTAM Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CRTAM data layer compared with 24 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher CRTAM Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CRTAM expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCS, STAD, and UCEC are the cancer types where CRTAM Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	All	0.007	0.689	<.001	24	view →
STAD	OS	Median	All	0.184	0.730	.001	21	view →
UCEC	DFS	Median	All	0.959	0.627	.025	6	view →
SKCM	OS	Median	All	0.217	0.781	.003	3	view →
COAD	OS	Median	All	0.433	0.873	.005	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CRTAM–UCS (OS)

Open the UCS breakdown →