Across TCGA patient cohorts, CRPPA RNA expression is significantly associated with the protein abundance of many other proteins, with 12,597 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRPPA-associated proteins across cancer lineages are LCP1_S257, DOK2, and THEMIS2. Each is linked with CRPPA in more than 4 cancer types. Because this analysis shows association rather than direction, both CRPPA-to-partner and partner-to-CRPPA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRPPA→partner) and Y-score (partner→CRPPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LCP1_S257 →	-0.868	-0.359	<.001	<.001	3	5
OV	DOK2 →	-0.527	-0.485	<.001	.001	3	4
GBM	THEMIS2 →	-0.421	-0.403	.004	.002	3	4
GBM	TNFAIP8 →	-0.667	-0.414	<.001	<.001	3	4
GBM	MYO1F →	-0.609	-0.420	<.001	<.001	3	4
GBM	NCF4 →	-0.693	-0.392	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,597 associations by consensus.

Exploration

CRPPA survival (RNA) · tumor vs normal (RNA) · all CRPPA data types