Across TCGA cell cohorts, CRPPA RNA expression is significantly associated with the RNA expression of many other genes, with 10,854 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CRPPA-associated genes across cancer lineages are CCN1, PDGFC, and ANKMY2. Each is linked with CRPPA in more than 8 cancer types. Because this analysis shows association rather than direction, both CRPPA-to-partner and partner-to-CRPPA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRPPA→partner) and Y-score (partner→CRPPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	CCN1 →	+3.990	+0.636	<.001	<.001	3	9
STOMACH	PDGFC →	+3.057	+1.111	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	ANKMY2 →	+1.034	+0.500	.002	.008	1	9
OVARY	SOSTDC1 →	+2.500	+0.539	<.001	.003	2	8
BONE	TNS3 →	+2.890	+0.659	<.001	<.001	3	7
BONE	KDELR2 →	+0.904	+0.751	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,854 associations by consensus.

Exploration

CRPPA survival (RNA) · tumor vs normal (RNA) · all CRPPA data types