CRNKL1

Across TCGA patient cohorts, CRNKL1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,761 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CRNKL1-associated genes across cancer lineages are GINS1, MCM8, and KRTCAP2. Each is linked with CRNKL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CRNKL1-to-partner and partner-to-CRNKL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRNKL1 versus GINS1 in LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRNKL1→partner) and Y-score (partner→CRNKL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GINS1 →	+1.116	+0.203	<.001	.002	3	8
LSCC	MCM8 →	+0.818	+0.378	<.001	<.001	3	8
GBM	KRTCAP2 →	+0.418	+0.321	<.001	<.001	3	8
GBM	EXO1 →	+1.439	+0.368	<.001	<.001	3	8
LSCC	TRMT6 →	+0.799	+0.349	<.001	<.001	3	8
LSCC	DARS2 →	+0.803	+0.406	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,761 associations by consensus.

CRNKL1 vs GINS1 — LUAD

Explore this scatter interactively →