CRNKL1

Across TCGA cell cohorts, CRNKL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,315 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CRNKL1-associated GO terms across cancer lineages are Regulation of peroxisome organization, Regulation by virus of viral protein levels in host cell, and RNA splicing, via transesterification reactions with bulged adenosine as nucleophile. Each is linked with CRNKL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CRNKL1-to-partner and partner-to-CRNKL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of peroxisome organization grouped by CRNKL1-low versus CRNKL1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRNKL1→partner) and Y-score (partner→CRNKL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of peroxisome organization →	+0.166	+0.757	<.001	<.001	3	8
KIDNEY	Regulation by virus of viral protein levels in host cell →	+0.161	+0.769	<.001	.003	3	8
SOFT_TISSUE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.065	+0.445	<.001	<.001	3	8
BREAST	Negative regulation of appetite by leptin-mediated signaling pathway →	+0.125	+0.889	<.001	<.001	3	8
SOFT_TISSUE	mRNA splicing, via spliceosome →	+0.065	+0.445	<.001	<.001	3	8
SKIN	mRNA export from nucleus →	+0.094	+0.654	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,315 associations by consensus.

Regulation of peroxisome organization by CRNKL1 expression — PANCREAS

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