CRLF3P2

Across TCGA pan-cancer cohorts, CRLF3P2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated CRLF3P2 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CRLF3P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CRLF3P2 expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

UVM, STAD, and BRCA are the cancer types where CRLF3P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.259	0.751	.010	36	view →
STAD	DFS	Tertile	IV	0.123	0.461	.009	21	view →
BRCA	DFS	Tertile	III,IV	0.133	0.496	.029	18	view →
OV	OS	Tertile	II,III,IV	0.204	0.332	.009	18	view →
KIRP	OS	Tertile	All	0.319	0.733	.007	15	view →
SKCM	DFS	Tertile	II,III,IV	0.262	0.599	.026	12	view →
LUSC	DFS	Tertile	All	0.809	0.629	.029	12	view →
READ	OS	Tertile	IV	0.289	0.899	<.001	9	view →
LGG	DFS	Tertile	All	0.386	0.771	.002	9	view →
LIHC	OS	Tertile	II,III,IV	0.226	0.769	.008	9	view →
ACC	DFS	Tertile	III,IV	0.089	0.468	.048	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

CRLF3P2–UVM (DFS)

Open the UVM breakdown →