CRLF3

Across TCGA patient cohorts, CRLF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,763 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CRLF3-associated proteins across cancer lineages are SUPT6H, BUB3, and LIG3. Each is linked with CRLF3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRLF3-to-partner and partner-to-CRLF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRLF3 versus SUPT6H in LSCC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF3→partner) and Y-score (partner→CRLF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SUPT6H →	+0.304	+0.600	<.001	<.001	3	5
GBM	BUB3 →	+0.227	+0.328	<.001	<.001	3	5
LSCC	LIG3 →	+0.505	+0.602	<.001	<.001	3	5
LSCC	SPAST →	+0.481	+0.439	<.001	<.001	3	5
LSCC	XRCC1 →	+0.298	+0.507	<.001	<.001	3	5
LSCC	BLMH →	+0.415	+0.515	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,763 associations by consensus.

CRLF3 vs SUPT6H — LSCC

Explore this scatter interactively →