CRLF3

Across TCGA patient cohorts, CRLF3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,757 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CRLF3-associated genes across cancer lineages are CSF2RB, BIN2, and GZMK. Each is linked with CRLF3 in more than 9 cancer types. Because this analysis shows association rather than direction, both CRLF3-to-partner and partner-to-CRLF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRLF3 versus CSF2RB in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF3→partner) and Y-score (partner→CRLF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CSF2RB →	+1.141	+0.468	<.001	<.001	3	10
OV	BIN2 →	+1.097	+0.554	<.001	<.001	3	10
OV	GZMK →	+1.383	+0.503	<.001	<.001	3	10
OV	CD48 →	+1.240	+0.493	<.001	<.001	3	10
UCEC	LY9 →	+0.756	+0.425	<.001	<.001	3	10
UCEC	ARHGAP9 →	+0.882	+0.401	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,757 associations by consensus.

CRLF3 vs CSF2RB — OV

Explore this scatter interactively →