CRLF3

Across TCGA patient cohorts, CRLF3 mutation is significantly associated with the RNA expression of many other genes, with 913 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRLF3-associated genes across cancer lineages are RN7SL472P, MIR4716, and RNU6-1318P. Each is linked with CRLF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRLF3-to-partner and partner-to-CRLF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL472P grouped by CRLF3-low versus CRLF3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF3→partner) and Y-score (partner→CRLF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL472P →	+0.821	+3.855	<.001	.003	3	2
BRCA	MIR4716 →	+0.468	+6.268	<.001	.001	3	2
UCEC	RNU6-1318P →	+0.296	+2.773	<.001	.004	3	2
UCEC	CTAGE15 →	+0.213	+2.278	.001	.008	3	1
UCEC	LINC02104 →	+0.254	+2.535	<.001	.003	3	1
UCEC	CWC25 →	+0.480	+2.839	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 913 associations by consensus.

RN7SL472P by CRLF3 expression — COAD

Explore this box plot interactively →