CRLF3

Across TCGA cell cohorts, CRLF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,460 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CRLF3-associated GO terms across cancer lineages are DNA strand elongation, DNA-templated DNA replication, and Nuclear division. Each is linked with CRLF3 in more than 14 cancer types. Because this analysis shows association rather than direction, both CRLF3-to-partner and partner-to-CRLF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation grouped by CRLF3-low versus CRLF3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF3→partner) and Y-score (partner→CRLF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DNA strand elongation →	+0.139	+0.976	<.001	<.001	3	15
LUNG_NSCLC_LUSC	DNA-templated DNA replication →	+0.101	+0.980	.006	.003	2	15
KIDNEY	Nuclear division →	+0.063	+0.708	<.001	<.001	3	14
BONE	Homologous recombination →	+0.119	+0.642	.005	.003	3	14
SOFT_TISSUE	Double-strand break repair →	+0.065	+0.399	<.001	.002	3	14
BONE	Chromosome segregation →	+0.110	+0.613	.005	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,460 associations by consensus.

DNA strand elongation by CRLF3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →