Across TCGA patient cohorts, CRLF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,086 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CRLF2-associated proteins across cancer lineages are CLIC2, ANKRD44, and MRC1. Each is linked with CRLF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CRLF2-to-partner and partner-to-CRLF2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF2→partner) and Y-score (partner→CRLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CLIC2 →	+0.477	+0.787	<.001	<.001	3	6
OV	ANKRD44 →	+0.408	+0.123	<.001	<.001	3	6
CCRCC	MRC1 →	+0.617	+0.208	<.001	<.001	3	6
LUAD	CLPX →	-0.307	-0.779	<.001	<.001	3	5
LSCC	PIP4K2A →	+0.438	+0.411	<.001	.001	2	6
LSCC	ARHGAP15 →	+0.501	+0.347	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,086 associations by consensus.

Exploration

CRLF2 survival (RNA) · tumor vs normal (RNA) · all CRLF2 data types