Across TCGA patient cohorts, CRLF2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible CRLF2-associated genes across cancer lineages are Erythrocytes, GMP, and Hepatocytes. Each is linked with CRLF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CRLF2-to-partner and partner-to-CRLF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF2→partner) and Y-score (partner→CRLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.031	+3.241	.012	.009	3	3
LUSC	GMP →	+0.037	+3.849	.023	.006	3	1
LUSC	Hepatocytes →	+0.012	+3.188	.009	.031	3	1
LUSC	MPP →	+0.009	+3.109	.018	.043	3	1
UCEC	Mesangial cells →	-0.042	-2.311	.031	.036	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

CRLF2 survival (RNA) · tumor vs normal (RNA) · all CRLF2 data types