Across TCGA cell cohorts, CRLF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,460 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CRLF2-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Negative regulation of viral process, and Urokinase plasminogen activator signaling pathway. Each is linked with CRLF2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CRLF2-to-partner and partner-to-CRLF2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF2→partner) and Y-score (partner→CRLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cytoplasmic pattern recognition receptor signaling pathway →	+0.072	+1.264	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Negative regulation of viral process →	+0.095	+0.776	<.001	.005	3	9
BLOOD_Lymphoma	Urokinase plasminogen activator signaling pathway →	+0.598	+0.732	.002	.005	3	8
LUNG_NSCLC_LUAD	Negative regulation of response to biotic stimulus →	+0.057	+0.780	.001	.002	3	8
BLOOD_Lymphoma	Antigen processing and presentation of peptide antigen via MHC class I →	+0.126	+1.054	<.001	.002	3	8
BLOOD_Lymphoma	Negative regulation of immune response →	+0.068	+1.037	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,460 associations by consensus.

Exploration

CRLF2 survival (RNA) · tumor vs normal (RNA) · all CRLF2 data types