Across TCGA cell cohorts, CRLF2 protein abundance is significantly associated with the RNA expression of many other genes, with 773 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CRLF2-associated genes across cancer lineages are FBLN2, ADNP, and SOX4. Each is linked with CRLF2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRLF2-to-partner and partner-to-CRLF2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF2→partner) and Y-score (partner→CRLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	FBLN2 →	-3.497	-1.600	<.001	.007	3	3
BLOOD_Lymphoma	ADNP →	-0.764	-1.578	.001	.008	3	3
BLOOD_Lymphoma	SOX4 →	-3.455	-2.559	.006	.004	3	3
SKIN	CLTRN →	-0.831	-1.253	.004	.003	3	3
SKIN	BHLHA15 →	+0.200	+1.077	.009	.006	2	4
BLOOD_Leukemia	KLLN →	-1.182	-0.984	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 773 associations by consensus.

Exploration

CRLF2 survival (RNA) · tumor vs normal (RNA) · all CRLF2 data types