CRLF1

Across TCGA patient cohorts, CRLF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,859 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CRLF1-associated proteins across cancer lineages are SERPINA1, KANK2, and LAMA4. Each is linked with CRLF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRLF1-to-partner and partner-to-CRLF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRLF1 versus SERPINA1 in CCRCC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF1→partner) and Y-score (partner→CRLF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SERPINA1 →	+0.607	+0.514	<.001	.001	3	5
BRCA	KANK2 →	+0.574	+0.995	<.001	<.001	3	5
CCRCC	LAMA4 →	+0.528	+0.622	<.001	.001	3	5
CCRCC	LMNA →	+0.508	+0.711	<.001	<.001	3	5
CCRCC	NID2 →	+0.601	+0.727	<.001	<.001	3	5
BRCA	COL4A2 →	+0.475	+0.908	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,859 associations by consensus.

CRLF1 vs SERPINA1 — CCRCC

Explore this scatter interactively →