CRLF1

Across TCGA patient cohorts, CRLF1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CRLF1-associated genes across cancer lineages are Platelets, CMP, and Macrophages. Each is linked with CRLF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRLF1-to-partner and partner-to-CRLF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by CRLF1-low versus CRLF1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLF1→partner) and Y-score (partner→CRLF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	Platelets →	+0.022	+4.121	.006	.028	3	2
LUAD	CMP →	+0.020	+3.577	.039	.015	3	2
UCEC	Macrophages →	+0.034	+3.498	<.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Platelets by CRLF1 expression — CESC

Explore this box plot interactively →