CRK

Across TCGA patient cohorts, CRK RNA expression is significantly associated with the protein abundance of many other proteins, with 12,394 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CRK-associated proteins across cancer lineages are YWHAE, ANKFY1, and UBE2G1. Each is linked with CRK in more than 8 cancer types. Because this analysis shows association rather than direction, both CRK-to-partner and partner-to-CRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRK versus YWHAE in OV, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRK→partner) and Y-score (partner→CRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YWHAE →	+0.440	+0.640	<.001	<.001	3	9
OV	ANKFY1 →	+0.301	+0.607	<.001	<.001	3	6
LSCC	UBE2G1 →	+0.319	+0.415	<.001	<.001	3	6
CCRCC	PRDX4 →	-0.405	-0.354	.001	<.001	3	5
OV	PAFAH1B1 →	+0.268	+0.456	<.001	<.001	3	5
LSCC	TSR1 →	+0.262	+0.373	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,394 associations by consensus.

CRK vs YWHAE — OV

Explore this scatter interactively →