CRK

Across TCGA patient cohorts, CRK protein abundance is significantly associated with the RNA expression of many other genes, with 9,562 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CRK-associated genes across cancer lineages are PAFAH1B1, TTC19, and INPP5K. Each is linked with CRK in more than 8 cancer types. Because this analysis shows association rather than direction, both CRK-to-partner and partner-to-CRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRK versus PAFAH1B1 in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRK→partner) and Y-score (partner→CRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PAFAH1B1 →	+0.527	+0.265	.002	.004	3	9
COAD	TTC19 →	+0.496	+0.166	.001	.006	3	7
OV	INPP5K →	+0.433	+0.219	<.001	<.001	3	7
OV	SAT2 →	+0.739	+0.326	<.001	<.001	3	7
COAD	GLOD4 →	+0.645	+0.259	<.001	<.001	3	7
BRCA	CYB5D2 →	+0.871	+0.249	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,562 associations by consensus.

CRK vs PAFAH1B1 — OV

Explore this scatter interactively →