CRISPLD2

Across TCGA patient cohorts, CRISPLD2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,496 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CRISPLD2-associated genes across cancer lineages are IL6, MEDAG, and IGDCC4. Each is linked with CRISPLD2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CRISPLD2-to-partner and partner-to-CRISPLD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRISPLD2 versus IL6 in CCRCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRISPLD2→partner) and Y-score (partner→CRISPLD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	IL6 →	+2.166	+0.666	<.001	.001	3	9
OV	MEDAG →	+2.151	+1.305	<.001	<.001	3	8
CCRCC	IGDCC4 →	+1.408	+0.765	<.001	<.001	3	8
OV	COL5A1 →	+2.477	+1.233	<.001	<.001	3	8
OV	GFPT2 →	+1.527	+1.190	<.001	<.001	3	8
GBM	CD300LB →	+0.786	+0.971	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,496 associations by consensus.

CRISPLD2 vs IL6 — CCRCC

Explore this scatter interactively →