CRISPLD1

Across TCGA patient cohorts, CRISPLD1 mutation is significantly associated with the RNA expression of many other genes, with 2,695 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRISPLD1-associated genes across cancer lineages are MIR615, DCAF13P2, and RNA5SP415. Each is linked with CRISPLD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRISPLD1-to-partner and partner-to-CRISPLD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR615 grouped by CRISPLD1-low versus CRISPLD1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRISPLD1→partner) and Y-score (partner→CRISPLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR615 →	+0.441	+4.279	<.001	<.001	3	4
LUSC	DCAF13P2 →	+0.085	+2.913	.002	.002	3	3
UCEC	RNA5SP415 →	+0.324	+1.711	.003	.008	3	3
LIHC	LINC01318 →	+0.099	+5.902	<.001	.001	3	2
UCEC	H2BC10 →	+0.400	+1.678	.009	.006	3	2
UCEC	RNA5SP412 →	+0.483	+1.896	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,695 associations by consensus.

MIR615 by CRISPLD1 expression — LUSC

Explore this box plot interactively →