CRIPT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRIPT RNA expression is significantly associated with the protein abundance of many other proteins, with 15,723 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CRIPT-associated proteins across cancer lineages are ZFR, RBM12, and GNL1. Each is linked with CRIPT in more than 4 cancer types. Because this analysis shows association rather than direction, both CRIPT-to-partner and partner-to-CRIPT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRIPT versus ZFR in HNSC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRIPT→partner) and Y-score (partner→CRIPT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCZFR →+0.243+0.430<.001<.00135
PDACRBM12 →+0.191+0.241.009.00335
LSCCGNL1 →+0.232+0.439<.001<.00135
GBMDHX9 →+0.217+0.641.001<.00135
HNSCGATAD2B →+0.293+0.607.001<.00135
GBMHNRNPU →+0.224+0.504.002<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,723 associations by consensus.

CRIPT vs ZFR — HNSC

Per-sample scatter of CRIPT vs ZFR in HNSC (Pearson r = 0.44).

Explore this scatter interactively →

Exploration