Across TCGA pan-cancer cohorts, CRIP3 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CRIP3 data layer compared with 25 for mass-spec protein and 4 for mutation status.
The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CRIP3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CRIP3 expression acts as an unfavorable survival marker.
CCRCC are the cancer types where CRIP3 mass-spec protein most reproducibly stratifies survival.