CRIP3

Across TCGA patient cohorts, CRIP3 mutation is significantly associated with the RNA expression of many other genes, with 338 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRIP3-associated genes across cancer lineages are MIR516B2, IFIT1P1, and IMP3P2. Each is linked with CRIP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRIP3-to-partner and partner-to-CRIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR516B2 grouped by CRIP3-low versus CRIP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRIP3→partner) and Y-score (partner→CRIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR516B2 →	+0.466	+3.708	<.001	.002	3	2
UCEC	IFIT1P1 →	+0.135	+3.714	.004	.003	3	2
SKCM	IMP3P2 →	+0.154	+2.851	<.001	.007	3	2
UCEC	CTHRC1P1 →	+0.111	+3.279	.003	.006	3	1
UCEC	IGHV3OR16-8 →	+1.029	+3.120	<.001	.001	3	1
UCEC	LINC02084 →	+0.545	+3.332	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

MIR516B2 by CRIP3 expression — UCEC

Explore this box plot interactively →